Effects of repeated injections of cloprostenol sodium during the early luteal phase on luteolysis and hormonal changes in Large White X Pietrain sows in Otukpo, Nigeria

This study was carried out to determine the effect of repeated injections cloprostenol sodium during early luteal phase on luteolytic capacity and hormonal changes Large white x Pietrain in Otukpo. A total ten (n = 10) oestrus sows were randomly divided into two groups. experiment a control. Group I 5) no synchronizing agent administered II received 6 doses 500 µg at days 5, 6, 7, 8, 9 10 oestrous cycle monitored for natural twice daily from 0700 – 1000 1500 1800h. The fertility parameters determined this were: Time onset (TOO), duration (DOO), litter size (TLS), born alive (TBA) average body weight (Av. BW). Five (5) milliliters blood collected via posterior vena cava before PGF2α day 1 9, every other afterwards till next observed oestrus. extracted serum assayed using competitive ELISA Oestradiol (E2) progesterone (P4) concentrations. Variables such as TOO, DOO, TLS, TBA, Av. BW data E2 P4 profile expressed mean ± SEM. Student ttest Tukey’s post-hoc test used compare percentages values between value P ≤ 0.05 considered significant. Results TOO 484.80 13.99 h, 15.92 h; DOO 86.40 5.88 h 76.80 4.80 TLS 10.00 0.84 10.20 0.66; TBA 0.55 1.26 0.09 kg 1.06 groups respectively. However, showed statistically (P 0.05) significant differences control treated concentrations samples first which is oestrus, fifth (PGF2α) 23rd